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Biology Colloquium/Tri-Beta Biology Club - Dr. Melissa Lodoe

PostPosted: Mon May 04, 2015 12:45 pm
by cdouglas

California State University, Fresno Department of Biology and Tri-Beta Biology Club presents

“Two sides of the coin: monocytes in immunity and pathogenesis”
By Dr. Melissa Lodoen, UC Irvine

Friday, May 8, 2015
3:00 PM in Science II Room 109




Toxoplasma gondii is a prevalent opportunistic pathogen that causes severe disease in immune compromised patients. A major goal of our research is to determine the molecular mechanisms that mediate the interactions between T. gondii and the host immune response. Monocytes are myeloid cells that are known to play an important role during T. gondii infection as both a host cell harboring the parasite and in immune defense against the infection. We are using primary human cell systems and in vivo models to investigate how T. gondii interacts with monocytes to potentiate parasite dissemination and to induce protective immunity.Ultimately our goal is to contribute novel insights into mechanisms of parasite pathogenesis to facilitate strategies to combat T. gondiiinfection and disease.

*If you need a disability-related accommodation or wheelchair access, please contact Lindasue Garner in the Department of Biology at 278-2001 or e-mail lgarner@csufresno.edu (at least one week prior to event).